Venous Leg Ulcers

The Effects of Low-frequency Nerve Stimulation to Support Healing of Venous Leg Ulcers

“With the support of an unrestricted educational grant from one of our industry partners* the Canadian Association of Wound Care initiated a review of the literature regarding the use of low-frequency nerve stimulation in the management of venous leg ulcers. The goal of the document was to provide an overview of the existing literature and establish protocols for

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Venous Leg Ulcers

Venous leg ulcers

A leg ulcer is defined as the loss of skin below the knee on the leg or foot, which takes more than 2 weeks to heal. Venous leg ulceration is due to sustained venous hypertension, which results from chronic venous insufficiency and/or an impaired calf muscle pump. Venous leg ulcers

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Venous Leg Ulcers

Protease-modulating matrix treatments for healing venous leg ulcers

First-line treatment for VLUs is compression therapy, but around 60% of people have unhealed ulcers after 12 weeks’ treatment and about 40% after 24 weeks; therefore, there is scope for further improvement. Limited evidence suggests non-healing leg ulcers may have persisting elevated levels of proteases, which is thought to deter

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